Author + information
- Kelly Nicol,
- Anthony Costa,
- Shubhika Srivastava and
- Santosh Uppu
Background: Morphological criteria that result in inducible ischemia with anomalous aortic origin of coronary artery (AAOCA) have been postulated but not confirmed. Computational fluid dynamics (CFD), finite element analysis (FEA) on virtual AAOCA three-dimensional models (3DM) could elucidate the mechanism of flow alteration. Our objective is to test feasibility creating 3DM of various AAOCA's and usable mesh for simulation analysis.
Methods: Data from CT angiograms (voxel size 0.6-0.9 mm) was transferred to Seg3D2 to be resampled and to isolate the AAOCA. Median filtering was used to remove noise while preserving edge integrity, followed by Otsu thresholding for segmentation and labeling of the AAOCA. Extraneous portions were manually deleted before application of a connected component filter. Final label maps (voxel size 0.2 mm) were transformed into mesh-based models with the marching cubes technique. Meshlab was used for visualization of the coronary ostia and course.
Results: Twelve 3DM & mesh models were successfully created using our method, visualization of the ostia and proximal intramural course was possible in these models (figure). This process took about 20 minutes each.
Conclusions: Rapid high resolution 3DM and usable mesh of AAOCA for simulation analysis using traditional cardiac CT data is feasible using our methods. This technique will lay the foundation for CFD and simulation of inducible ischemia using FEA analysis.
Poster Hall, Hall C
Saturday, March 18, 2017, 3:45 p.m.-4:30 p.m.
Session Title: Congenital Heart Disease: New Diagnostic Approaches in Congenital Heart Disease
Abstract Category: 10. Congenital Heart Disease: Pediatric
Presentation Number: 1231-019
- 2017 American College of Cardiology Foundation