Author + information
- Odilson Marcos Silvestre,
- Daniel Addison,
- Samson Okello,
- Siddique Abbasi and
- Harvard T.H. Chan
Background: Natural disasters are becoming increasingly common worldwide. Whether these disasters are directly associated with higher rates of myocardial infarction (MI) is unclear.
Methods: Searching the PUBMED, EMBASE, and LILACS databases from inception through August 7, 2016 we selected all studies focusing on the incidence of myocardial infarction within 1 year of a natural disaster (earthquake, flood, hurricane, or tornado). We included studies comparing MI incidence before and after the occurrence of a disaster across equivalent time intervals. Quantitative data synthesis was performed using a random effects model with heterogeneity assessed using I2 statistics. In addition, meta-regression analysis was performed to assess the impact of disaster magnitude on MI rates among earthquake victims.
Results: A total of 21 disasters (16 earthquakes) affecting >20,000,000 persons were included. Natural disasters were associated with higher risk of MI with 6,294 post-disaster events compared to 5,901 pre-disaster (OR 1.32 (1.15-1.51), I2=76%). Among disaster subgroups, earthquakes were associated with a higher risk of MI (OR 1.42 (1.20-1.67)). Further, earthquake magnitude was linearly associated with risk of MI (p=0.002; see figure).
Conclusions: In a meta-analysis of ecological studies, natural disasters are associated with an increased risk of MI. Among those affected by earthquakes, magnitude appears to influence this association.
Poster Hall, Hall C
Friday, March 17, 2017, 10:00 a.m.-10:45 a.m.
Session Title: Traditional and Novel Factors Used to Assess the Risk of, and Used for the Treatment of, Coronary Artery Disease
Abstract Category: 2. Acute and Stable Ischemic Heart Disease: Clinical
Presentation Number: 1126-326
- 2017 American College of Cardiology Foundation