Author + information
- Mary Fishera,b,
- Gbolahan Ogunbayoa,b,
- Ameer Musaa,b,
- Odunayo Olorunfemia,b,
- Ayman Elbadawia,b,
- Deola Saheeda,b and
- Bennet Georgea,b
Background: There is limited data on outcomes of heart failure (HF) hospitalizations in patient with Human Immunodeficiency Virus (HIV). Our study describes epidemiological characteristics regarding patients with HIV admitted with a primary diagnosis of heart failure over a 16 year period in the United States and highlights major clinical outcomes.
Methods: Using the Nationwide inpatient database, we identified patients admitted with a primary diagnosis of heart failure and a Clinical Classifications Software diagnosis of HIV. We identified patients by race (White, Black, Hispanic, Asian, and Other) and described patient characteristics, interventions, and hospital outcomes. We performed logistic regression analysis with mortality as the primary outcome.
Results: Of the 782,715 HIV patients admitted between 1998 and 2013, 11,193 (1.4%) was for a primary diagnosis of heart failure. Most patients (75%) were between the age of 40 and 64 on admission. The highest burden of disease between the age of 18 and 64 was identified in the black population (p value =.001 in patients 18-39 and p value= .014 in patients between age 40 and 64), while among patients over 65 years, the highest burden of the disease was among white patients (18.6%, p value =.001). There was a disproportionately higher number of males with HIV admitted for HF. Two hundred and thirty (2.1%) patients died during their hospitalization. Mortality was higher in the male population (72.2%, p=.007), highest among Whites (3.3%) and lowest in Blacks (1.8%) (p=.009). Race was not independently associated with a higher risk of mortality. There was no statistical difference in in-hospital complications (cardiogenic shock, respiratory failure, acute renal failure, pneumonia, stroke/TIA and cardiac arrest) or number or procedures among all groups. After controlling for age, gender and comorbidities, renal failure (OR: 1.7; 95%CI: 1.1-2.6; p=.015) was an independent predictor of mortality.
Conclusions: The burden of CHF in patients with HIV is highest among black and higher in the male gender. In HIV patients admitted for heart failure, renal failure was an independent predictor of mortality.
Poster Hall, Hall C
Friday, March 17, 2017, 10:00 a.m.-10:45 a.m.
Session Title: Population Specific Cardiomyopathies: From Exomes to Databases
Abstract Category: 12. Heart Failure and Cardiomyopathies: Basic
Presentation Number: 1122-257
- 2017 American College of Cardiology Foundation