Author + information
- Nir Uriel,
- Gabriel Sayer,
- Gene Kim,
- Sirtaz Adatya,
- Nitasha Sarswat,
- Jayant Raikhelkar,
- Teruhiko Imamura,
- Daniel Rodergs,
- Ronnie Abbo and
- Daniel Burkhoff
Background: Remote dielectric sensing (ReDS) measuring lung fluid content, expressed as a percent of lung volume is being studied to monitor fluid status in heart failure (HF) patients to reduce hospitalizations. However, the correlation between ReDS values and invasive measures of volume status is unknown.
Methods: HF patients undergoing right heart catheterization were prospectively enrolled and assessed with concomitant ReDS readings. Correlations between ReDS readings with central venous and pulmonary capillary wedge pressures (CVP and PCWP, respectively) were assessed. Sensitivity and specificity of determining elevated pressures indicative of fluid overload were assessed using ROC analysis.
Results: 58 patients with 70 concomitant measurements were enrolled. Mean age was 55.9 ± 12.9, 82% were male. A strong correlation was found between ReDS values and PCWP (r=0.63), CVP (r=0.58) and CVP+PCWP (r=0.65). ROC curve analysis revealed that a ReDS value ≥35% predicted a PCWP ≥18 mmHg with an AUC of 0.88, sensitivity of 0.88 and specificity of 0.83 (Fig 1A). There were progressive increases in ReDS (Fig 1B) with isolated CVP elevations >12 mmHg, isolated PCWP elevations >18 mmHg and combined CVP and PCWPs (p<0.05).
Conclusions: ReDS correlated with CVP and PCWP. In light of the high sensitivity and specificity of a ReDS score ≥35% to detect abnormally high filling pressures, the ReDS system can provide a simple noninvasive means of early detection of episodes of decompensated HF.
Poster Hall, Hall C
Friday, March 17, 2017, 3:45 p.m.-4:30 p.m.
Session Title: Acute Heart Failure: Evaluating Strategies to Prevent Readmissions
Abstract Category: 13. Heart Failure and Cardiomyopathies: Clinical
Presentation Number: 1163-287
- 2017 American College of Cardiology Foundation