Author + information
- Erifili Venieri,
- Constantina Aggeli,
- Aris Anastasakis,
- Elisavet Sfendouraki,
- Christodoulos Stefanadis and
- Dimitris Tousoulis
Background: There is growing evidence that the mitral apparatus in hypertrophic cardiomyopathy (HCM) has primary structural abnormalities. The objective of this study was the assessment of the mitral valve in patients (pts) with HCM using 2D and Real-Time 3D Transesophageal Echocardiography (RT3DTEE).
Methods: Transthoracic and 2D-RT3DTEE study, were performed in 55 HCM pts and 28 controls. Group I included 37 pts with the non-obstructive pattern, while group II 18 pts with LVOT obstruction. The mitral valve 3D datasets were analyzed offline at end-systole.
Results: Group I (mean age 46 ± 17 years, 25 males), Group II (mean age 50 ± 15 years, 10 males), Control Group (mean age 49 ± 12 years, 13 males). The mean interventricular septum width was 19.3±3.42 mm in Group I, 21.06±4.04 mm in Group II and 9.1±1.08 mm in the Control Group, p<0.05. The peak LVOT pressure gradient in Group II was 58±25 mmHg. The results of the 2D-RT3DTEE study are shown in the table.
Conclusions: The mitral valve in pts with HCM appears to have unique morphology, such as larger annular height, narrower aortomitral angle and longer leaflets. Furthermore the anterior displacement of the coaptation line in pts with obstruction combined with a larger tenting height of the leaflets in systole seems to contribute to the LVOT obstruction. These primary changes of the mitral valve offer new data on the anatomy and the pathophysiology of the disease.
Poster Hall, Hall C
Saturday, March 18, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Advances in HCM, PPCM and Other Cardiomyopathies
Abstract Category: 13. Heart Failure and Cardiomyopathies: Clinical
Presentation Number: 1201-280
- 2017 American College of Cardiology Foundation