Author + information
- Lorraine S. Evangelistaa,b,
- Dawn Lombardoa,b,
- Tamara Horwicha,b,
- Michele Hamiltona,b and
- Gregg Fonarowa,b
Background: There is controversy over dietary protein's effect on long-term chronic disease risks in obese patients with heart failure (HF). The aim of this RCT was to compare the effects of two calorie-restricted diets differing in protein content on chronic disease risks.
Methods: Ninety-seven obese (mean BMI, 37 ± 6 kg/m2) patients with HF, aged 59 ± 9 years, 70% males, consumed two diets, each for 12 weeks. The diets were: (1) a high protein diet (HP, 30% protein, 40% carbohydrates, and 30% fat) and (2) a standard protein diet (SP, 15% protein, 55% carbohydrates, and 30% fat). Their effects on weight, glycemic control, lipid profiles, and blood pressure at the beginning and end of each dietary intervention were analyzed.
Results: Both diets were equally effective in promoting weight and visceral fat loss and in improving total cholesterol (TC), but the HP diet decreased to a greater extent HgbA1C levels (P < 0.001) when compared with the SP diet. The HP diet improved significantly triglyceride (TG) levels (P < 0.001) and both systolic and diastolic blood pressures when compared with the SP diet (both P < 0.001), see figure). No differences were noted in LDL and HDL levels.
Conclusions: Energy restricted diets facilitate weight loss and visceral fat loss and lower in obese patients with HF. However, the HP diet promoted better improvements in TG, HgbA1C, and blood pressure than the SP diet, and may be superior in reducing chronic disease risks and potentially slowing the progression of disease in this population.
Poster Hall, Hall C
Saturday, March 18, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Advances in HCM, PPCM and Other Cardiomyopathies
Abstract Category: 13. Heart Failure and Cardiomyopathies: Clinical
Presentation Number: 1201-290
- 2017 American College of Cardiology Foundation