Author + information
- Karina Auristela Gonzalez Carta,
- Ivan Mendoza,
- Igoor Morr,
- Ivan Mendoza,
- Francesca Misticchio,
- Yolimar Meza,
- Vicente Finizola,
- Gerardo Chazzin and
- Juan Marques
Backround: Zika virus infection is a mosquito-borne disease that has caused an explosive pandemic throughout the Americas. Local transmission has been found in USA; there are no reports of cardiovascular (CV) manifestation of Zika. This study sought to describe the occurrence of CV involvement of Zika.
Methods: We enrolled 9 cases of Zika from a Venezuelan outbreak who had exhibited CV manifestations in a prospective observational multicenter study. Clinical, ECG, laboratory (including virological studies), Rx, echocardiogram, Holter and cMRI evaluation were performed.
Results: Of the 9 patients, 6 were female with a mean age of 47 ± 17 years. Arrhythmias were detected in 8 patients including acute atrial fibrillation in 3 cases, 2 paroxysmal and 1 persistent, non-sustained atrial tachycardia in 2 patients and ventricular arrhythmias in 2 patients. Heart failure was present in 6 cases, 5 with low ejection fraction (EF), and one with preserved EF, with pre-eclampsia and moderate to severe pericardial effusion.
Conclusions: This is the first report of cardiac involvement in patients with Zika. Physicians should be aware of the possibility of cardiac manifestations. Studies are needed to define the incidence of myocarditis systematically.
Poster Hall, Hall C
Saturday, March 18, 2017, 3:45 p.m.-4:30 p.m.
Session Title: Emerging Developments in HFpEF and Arryhthmias
Abstract Category: 13. Heart Failure and Cardiomyopathies: Clinical
Presentation Number: 1250-293
- 2017 American College of Cardiology Foundation