Author + information
- Diego Araiza Garaygordobil,
- Edgar Alexander Illescas González,
- Luis Marroquin Donday,
- Aloha Meave,
- Erick Alexanderson Rosas and
- Gabriela Melendez Ramirez
Background: Chagas’ disease is a serious problem in Latin America. Clinical settings where is managed might be limited; therefore simple diagnostic tools are needed to improve detection. Goldberger's electrocardiographic triad (SV1 or SV2 + RV5 or RV6 ≥ 3.5 mV, total QRS amplitude in limb leads ≤ 0.8 mV and R/S ratio < 1 in V4) has been described as a marker of left ventricular (LV) dysfunction. The aim of this study was to evaluate the utility of Golbderger's triad in predicting LV dysfunction in patients with Chagas’ heart disease.
Methods: Retrospective chart review of seropositive patients for Chagas’ disease whom underwent cardiac magnetic resonance in our hospital. Both asymptomatic and symptomatic patients were included. EKG's were blindly assessed in search of Goldberger's triad and results were compared with LVEF determined by CMR.
Results: 42 patients were found. No patient in our study fulfilled the criteria described by Goldberger. Independent analysis of each criterion (Table 1) showed that poor R wave progression (third criterion) was significantly associated with a LVEF <40% (p = <.001, Se: 53%, Sp: 100%). Combinations of the rest Goldberger's criteria didn't render any improvement in statistic precision.
Conclusions: In patients with Chagas’ disease, Goldberger's electrocardiographic triad is an insensitive marker of systolic dysfunction; however, poor R wave progression (Goldberger's third criterion) is a highly specific marker of left ventricular failure.
Poster Hall, Hall C
Saturday, March 18, 2017, 3:45 p.m.-4:30 p.m.
Session Title: Emerging Developments in HFpEF and Arryhthmias
Abstract Category: 13. Heart Failure and Cardiomyopathies: Clinical
Presentation Number: 1250-294
- 2017 American College of Cardiology Foundation