Author + information
- Yoshiyuki Yazaki,
- Hiroki Niikura,
- Norihiro Kogame,
- Masahide Tokue,
- Nobutaka Ikeda,
- Raisuke Iijima,
- Hidehiko Hara,
- Masao Moroi and
- Masato Nakamura
Background: Obesity is associated with incident heart failure, but it is paradoxically associated with better prognosis during acute heart failure(AHF). Currently, obesity is usually identified by body mass index(BMI). Bioelectrical impedance analysis is a noninvasive modality for evaluating the body fat percentage(FAT%). The aim of this study was to investigate whether FAT% provides prognostic value in patients with AHF.
Method and Results: This study enrolled 139-patient(mean ages 75.6years, male 64.0%) admitted for AHF between November 2013 and January 2015 in our hospital. Etiology was ischemic in 19.4% and mean left ventricular ejection fraction(LVEF) was 47.3%. At their first visit, we evaluated FAT% by bioelectrical impedance analysis. 6-month outcomes focused on the events of rehospitalization. Median FAT% was 25.3%(IQR 15.2-34.3). We divided to two groups according median of FAT%. The result showed in the figure. After adjustment for covariates including age, male, NYHA, eGFR, BMI, LVEF and NT-proBNP, multivariate cox regression analysis identified that Low FAT% was an independent predictor of rehospitalization (HR 3.00,95% CI 1.03-8.75, p=0.044).
Conclusions: FAT% by bioelectrical impedance during the first assessment of AHF identified those carrying a worse medium-term prognosis. Patients in Low FAT% were independently associated with an increased risk of rehospitalization at 6-month. This association would explain “obesity paradox”.
Poster Hall, Hall C
Sunday, March 19, 2017, 9:45 a.m.-10:30 a.m.
Session Title: The Evolving World of LVADs, Transplant and Other Novel Discoveries
Abstract Category: 13. Heart Failure and Cardiomyopathies: Clinical
Presentation Number: 1294-265
- 2017 American College of Cardiology Foundation