Author + information
- Amitoj Singh,
- Sahil Agrawal,
- Lohit Garg,
- Mark Fegley,
- Sabir Saluja,
- Sudip Nanda and
- Jamshid Shirani
Background: Chagas’ disease (CD), caused by Trypanosoma cruzi, has been increasingly diagnosed as a cause of cardiovascular disease in the US. We aimed to examine trends of hospital admissions and cardiovascular outcomes of CD.
Methods: Search of 2003-2011 Nationwide Inpatient Sample database identified 949 (age 57±16 years, 51% male, 67% Hispanic) admissions for CD.
Results: A trend at increasing number of admissions for CD was noted during the study period (OR=1.054; 95% CI=1.028-1.081; p<0.0001); 72% were admitted to Southern and Western hospitals. Comorbidities included hypertension (40%), CAD (28%), hyperlipidemia (25%), tobacco use (12%), diabetes (9%), heart failure (5%) and obesity (2.2%). Cardiac abnormalities noted during hospitalization included atrial fibrillation (27%), ventricular tachycardia (23%), SA node dysfunction (5%), complete heart block (4%), valvular heart disease (6%)] and LV aneurysms (5%). In-hospital mortality was 3.2%. Other major adverse events are listed in Table 1. Overall, 63% suffered at least one adverse event. Temporary (2%) and permanent (3.5) pacemaker or ICD (10%), mechanical circulatory support (3.1%) or cardiac transplant (2.1%) were needed for in-hospital management.
Conclusions: Despite remaining concerns about lack of awareness of CD in the US, a steady number of hospital admissions were reported from 2003-2011. Cardiovascular disease was highly prevalent in these patients and was frequently associated with fatal and non-fatal complications.
Poster Hall, Hall C
Sunday, March 19, 2017, 9:45 a.m.-10:30 a.m.
Session Title: The Evolving World of LVADs, Transplant and Other Novel Discoveries
Abstract Category: 13. Heart Failure and Cardiomyopathies: Clinical
Presentation Number: 1294-289
- 2017 American College of Cardiology Foundation