Author + information
- Rahat Muslem,
- Sakir Akin,
- Alina Constantinescu,
- Olivier Manintveld,
- Ozcan Birim,
- Ad J.J.C. Bogers and
- Kadir Caliskan
Background: Device failure can occur due to mechanical or biological complications. In this study, we investigated the incidence and predictors of Mechanical Device Failure (MDF) in Continuous-Flow Left Ventricular Assist Device (CF-LVAD) patients.
Methods: We conducted a retrospective study of all CF-LVADs (HeartMate II) implanted in our Centre (age>16). MDF was defined as a mechanical problem resulting from a driveline or inflow- outflow graft damage, an electrical problem, or as a drive unit/motor failure.
Results: A total of 69 CF-LVADs were implanted in 59 patients (mean support time of 528 ± 466 days, mean age 50.1±10.7 years, 75% male). MDF occurred in nine CF-LVADs at a mean time to event of 995 ± 371 days after implantation. The cumulative prevalence after 5 years of follow-up was 0%, 4%, 9%, 12%, and 13% (figure 1A). Patients who experienced MDF were longer supported by their LVAD (846 days (IQR: 708-1337) vs. 290 days (IQR: 142-620, P = 0.001), had more often their LVAD controllers exchanged (P=0.02) and also, the number of patients with a damaged or fractured driveline was significantly higher (p<0.001). MDF accounted for 17% of the deaths.
Conclusions: Patients needing extended CF-LVAD-support or with a history of technical problems are at risk for MDF. More intensive regular inspections of the CF-LVAD should be considered beyond 18 months of LVAD support.
Poster Hall, Hall C
Sunday, March 19, 2017, 9:45 a.m.-10:30 a.m.
Session Title: The Evolving World of LVADs, Transplant and Other Novel Discoveries
Abstract Category: 13. Heart Failure and Cardiomyopathies: Clinical
Presentation Number: 1294-293
- 2017 American College of Cardiology Foundation