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Background: Relationship between clinical frailty and mortality in patients with critical limb ischemia was not investigated.
Methods: This study was single center retrospective study. From October 2004 to March 2015, 829 patients (523 male,1085 limbs) underwent revascularization for patients with CLI (EVT:615 patients, bypass:214 patients). We categorized three groups (mild; CFS 1 to 3, moderate; CFS 4 to 6, severe; CFS 7 to 9). The outcome measures were overall survival (OS), amputation free survival (AFS) and limb salvage (LS).
Result: At 5 years, OS and AFS rates were significant difference between three groups (mild; 20.4% and 63.0%, moderate; 30.7% and 50.0%, severe; 41.8% and 41.4%, respectively) (p < 0.01, log-rank test).
On multivariate analysis by Cox proportional hazard ratio, severe CFS (hazard ratio, 1.63,95% confidential interval. 1.19-2.20; adjusted P=0.002) and hemodialysis, age>75 years, albumin<3g/dL, ejection fraction<50% were independent predictor of overall survival.
We also compared patients who underwent EVT with who underwent bypass procedure about each three groups, there was no differences in mortality at 5 years (mild group: hazard ratio,1.25, 95% confidential interval. 0.73-2.12; adjusted P=0.42, moderate group: hazard ratio,1.19,95% confidential interval. 0.72-2.00; adjusted P=0.49, severe group: hazard ratio,1.48,95% confidential interval. 0.88-2.59; adjusted P=0.15)
Conclusions: There were deep relationship between CLI and CFS
Moderated Poster Contributions
Interventional Cardiology Moderated Poster Theater, Poster Hall, Hall C
Sunday, March 19, 2017, 9:45 a.m.-9:55 a.m.
Session Title: Peripheral Arterial Disease, Risk, and Outcomes
Abstract Category: 18. Interventional Cardiology: Carotid and Endovascular Intervention
Presentation Number: 1306M-03
- 2017 American College of Cardiology Foundation