Author + information
- Rafael A. Meneguz-Moreno,
- Jose de Ribamar Costa,
- Nisia Gomes,
- Auristela Ramos,
- Alfredo Ferreira Neto,
- Dimytri Siqueira,
- Mercedes Maldonado,
- Zilda Meneghelo,
- Cesar Esteves,
- Sergio Braga,
- Amanda Sousa and
- Alexandre Abizaid
Background: Data on long-term outcomes of percutaneous balloon mitral valvuloplasty (PMV) are still scarce. We sought to access immediate and very long late events after PMV.
Methods: We prospectively enrolled 1,582 patients who underwent PMV from 1987 to 2011 at a single-center. The primary endpoint was the incidence of major adverse cardiac events (MACE), including all-cause mortality, need for mitral surgery or repeat PMV up to 23 years after the procedure.
Results: Procedural success was achieved in 90.8% of all patients. At multivariate analysis, the independent predictors of success were left atrium size (HR: 0.96, 95% CI: 0.93-0.99, p=0.045), Wilkins-score <8 (HR: 0.60, 95% CI: 0.48-0.93, p=0.02) and age (HR: 0.97, 95% CI: 0.96-0.99, p=0.006). Long-term follow-up (mean 15.6 ± 4.9 years) was obtained in 68% of cases. Success rates were not different throughout the 23 years. The incidence of the primary endpoint was 19.1% (95% CI: 17.0-21.1). The rates of all-cause mortality, need for mitral surgery or repeat PMV were 0.6% (95% CI: 0.3-1.2), 8.3% (95% CI: 7.0-9.9) and 10.0% (95% CI: 8.5-11.7), respectively (Fig. 1).
Conclusions: Up to 23 years successful PMV, more than three quarters of all patients still exhibit sustained results and the immediate outcomes were not different throughout this single-center study experience.
Moderated Poster Contributions
Interventional Cardiology Moderated Poster Theater, Poster Hall, Hall C
Sunday, March 19, 2017, 1:15 p.m.-1:25 p.m.
Session Title: Frontiers in Mitral Valve Disease and Treatment
Abstract Category: 24. Interventional Cardiology: Mitral and Structural Heart Disease
Presentation Number: 1316M-09
- 2017 American College of Cardiology Foundation