Author + information
Atherosclerotic peripheral arterial disease (PAD) is one of the most prevalent, morbid, and mortal diseases. The aim of this study was to evaluate 2 years mortality rates of patients with atherosclerotic PAD treated endovascular treatment.
This study is a single-center, prospective observational study. Between October 2011 and August 2014, we enrolled 233 patients (191 men; 73 ± 9 years) with symptomatic PAD were treated by endovascular intervention. Those subjects were evaluated baseline characteristics, 2 years mortality and cardiovascular events. And we estimated predictors of 2 years mortality.
Baseline characteristics were smoking history 73%, hypertension 71%, dyslipidemia 46%, diabetes 55%, coronary artery disease 66%, and chronic kidney disease 62%, and dialysis 16%, critical limb ischemia 31%. LDL-C 102 ± 30 mg/dL, HbA1c 7.0 ± 3.6%, eGFR 60 ± 19 mL/min./1.73 m2. Medication record (Aspirin 38%, Clopidogrel 40%, Cilostazol 55%, and Statin 42%). Mortality and cardiovascular event rates were 12% and 19% at 2 years post procedure. Multivariate analysis (Cox proportional hazards regression analyses) estimate that dialysis and critical limb ischemia are predictors of mortality (Odds ratio: dialysis 4.73, p＜0.05, critical limb ischemia 6.14, p＜0.05).
Mortality of peripheral vascular disease was 12% at 2 years post endovascular treatment. Dialysis and critical limb ischemia were predictors of mortality in symptomatic PAD.