Author + information
- Received May 21, 1985
- Revision received October 15, 1985
- Accepted October 31, 1985
- Published online March 1, 1986.
- Harvey G. Kemp, MD, FACC†,
- Richard A. Kronmal, PhD‡,a,
- Ronald E. Vlietstra, MD, FACC§,
- Robert L. Frye, MD, FACC§,
- Coronary Artery Surgery Study*
- ↵aAddress for reprints: Richard A. Kronmal, PhD, CASS Coordinating Center, University of Washington, 1107 Northeast 45th, Room 530, Seattle, Washington 98105.
The effect on 7 year survival of having a normal or near normal coronary arteriogram was examined using data from the CASS registry of 21,487 consecutive coronary arteriograms taken in 15 clinical sites. Of these, 4,051 arteriograms were normal or near normal, and the patients had normal left ventricular function as judged by absence of a history of congestive heart failure, no reported segmental wall motion abnormality and an ejection fraction of at least 50%; 3,136 arteriograms were entirely normal and the remaining 915 revealed mild disease with less than 50% stenosis in one or more segments. The 7 year survival rate was 96% for the patients with a normal arteriogram and 92% for those whose study revealed mild disease (p < 0.0001). Nine risk variables recorded at entry were analyzed for predictive value for survival: age, sex, height, weight, history of smoking, presence or absence of mild disease, electrocardiographic response to exercise, family history of coronary heart disease and a history of hypertension. Of these, age, smoking history, presence or absence of disease and a history of hypertension had predictive value.
↵* A list of participating clinical sites and investigators appears in the Appendix.
The Collaborative Study in Coronary Artery Surgery is funded by the National Heart, Lung, and Blood Institute, Bethesda, Maryland.
- Received May 21, 1985.
- Revision received October 15, 1985.
- Accepted October 31, 1985.
- American College of Cardiology Foundation