Author + information
- Received October 21, 1985
- Revision received January 10, 1986
- Accepted January 23, 1986
- Published online June 1, 1986.
- Roxann Rokey, MD, FACCa,
- Leroy L. Sterling, MD,
- William A. Zoghbi, MD,
- Michele P. Sartori, MD,
- Marian C. Limacher, MD, FACC,
- Lawrence C. Kuo, MD and
- Miguel A. Quinones, MD, FACC
- ↵aAddress for reprints: Roxann Rokey, MD, Baylor College of Medicine, One Baylor Plaza, Room 512 D, Houston, Texas 77030.
Measurements of mitral and aortic valve flows were obtained with two-dimensional Doppler echocardiography in 25 patients with isolated mitral (n = 19) or aortic (n = 6) regurgitation and regurgitant fraction was calculated as the difference between the two flows divided by the flow through the regurgitant valve. Results were compared with measurements of regurgitant fraction determined by combined left ventricular angiography and thermodilution. Regurgitant fraction averaged 56 ± 18% (range 19 to 79) by Doppler echocardiography and 48 ± 17% (range 13 to 72) by angiography. A significant correlation was observed between the two methods (r = 0.91; SEE = 7 %). In contrast, no significant correlation was found between regurgitant fraction measured by either method and the angiography 1+ to 4+ qualitative classification of regurgitation. Doppler echocardiography appears to be an accurate method for the noninvasive quantification of severity of regurgitation in isolated left-sided valve lesions.
This paper was presented in part at the 57th Annual Scientific Session of the American Heart Association, Miami, Florida, November 1984. Computational assistance was provided by the CLINFO Project funded by Grant RR-00350 from the Division of Research Resources, National Institutes of Health, Bethesda, Maryland.
- Received October 21, 1985.
- Revision received January 10, 1986.
- Accepted January 23, 1986.
- American College of Cardiology Foundation