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To investigate the efficacy and safety of different modes of exercise rehabilitation among patients with ACS (acute coronary syndrome) undergoing PCI (percutaneous coronary intervention) and explore the optimal mode of these patients.
Between April 2015 and August 2016, a total of 33 patients with ACS after stent implementation in the department of cardiology of General Hospital of Shenyang Military Region were enrolled. Patients were assigned to unsupervised exercise group (n=18, self-exercise rehabilitation) and supervised exercise group (n=15, exercise rehabilitation under physician direction) based on modes of exercise rehabilitation. The training program in supervised exercise group was 40 minutes of aerobic exercise on a treadmill and exercise bike 3 to 5 times per week at least 3 months. The exercise intensity was based on the heart rate corresponding to anaerobic threshold. A symptom limited cardiopulmonary exercise testing (CPET) was performed pre- and post-exercise to compare the efficacy of different modes.
Comparing with pre-exercise, all patients had significantly higher of VO2 peak/kg and MVV% (maximal voluntary ventilation) post-exercise (14.98±3.29 vs 19.42±7.37, 93.85±22.56 vs 112.79±27.24, both P<0.05, respectively). Among the patients supervised, the VO2 peak/kg and MVV% had a significant improvement between pre- and post-exercise (14.41±3.29 vs 21.33±8.88, 94.87±25.44 vs 114.87±24.97, both P<0.05, respectively). Nevertheless, there was no significant difference in unsupervised exercise group. No adverse cardiovascular events were observed during the exercise both groups.
The present study demonstrated that exercise rehabilitation could increase exercise tolerance in patient with ACS undergoing PCI. Supervised Exercise rehabilitation might improve the prognosis of patients more significantly and should be recommended.