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To evaluate the incidence of contrast induced acute kidney injury for coronary artery disease(CAD) in diabetes Patients with percutaneous coronary intervention(PCI) more than once during short periods of Injection of Contrast Medium.
A retrospective review was performed on 612 acute coronary syndrome patients who underwent PCI more than once in a month in our department from January 2006 to January 2015. The patients were divided into two groups: diabetes group (149 cases) and non-diabetic group (463 cases). Compared the baseline clinical features, laboratory data, the related risk factors and the incidence rate of CI-AKI between the two groups. Major adverse cardiac events (MACE) including cardiac death, revascularization restenosis, acute myocardial infarction (AMI), stent thrombosis and Minor adverse events including the deterioration of renal function and cerebral infarction were followed up during one year. Adopting Logistic Regression analysis the related risk factors of CI-AKI.
Age, the incidence of hypertension, the incidence of CHD and numerous of cerebral vascular disease in the diabetic group was significantly higher than non-diabetic group (P=0.001, P<0.001, P=0.004, P=0.05); but other clinical features isn't differences (P>0.05). Compared with the non-diabetes group, the used of beta blockers drug and the ratio of the multi vessel disease (P<0.01) in diabetes group is higher (P<0.05),. The incidence rate of CI-AKI during hospitalization and follow-up in the diabetic group were higher than them the non-diabetes group, but the differences were not statistically significant (P1=0.272, P2=0.193) There wasn't the correlation independent factor risks between diabetes and CI-AKI (P>0.05); The rate of MACE in diabetes mellitus group was obviously higher than the non-diabetes group (P=0.005).
Diabetes was not the independent risk factors for CI-AKI, diabetic patients who underwent CAG and PCI more than once during short periods of Injection of Contrast Medium had higher the accident rate of MACE.