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To investigate the differences of prognosis in female patients with different age after percutaneous coronary intervention (PCI).
Between January 2010 and December 2014, 36107 patients underwent coronary angiography, among them, 35802 patients with complete information admitted. The elderly group(>=65) have 5573 patients and the middle-aged group have 5173 patients. The major adverse cardiac and cerebral events MACCE events, mortality, target vessel revascularization(TVR), bleeding events, bleeding from the academic research BARC2-5, BARC3-5 after 30 days and 1 year have been compared between the two groups.
The proportion of patients with smoking, hypertension, chronic myocardial infarction proportion is higher in the elderly group than the middle-aged group [13.6% (757/5573) vs 10.9% (564/5179), 70.5% (3927/5573) vs 59.2% (3068/5179), 13.4% (450/5179) (749/5573) vs 8.7%)]. The mean of left ventricular ejection fraction in the elderly group is lower than the middle-aged group [(0.63 + 0.82) vs (0.64 + 0.07)]. The proportion of patients accepted coronary angiography and PCI through flexible artery path in the elderly group is significant higher than the middle-aged group (46.7% vs 40.7 %, P < 0.001). The amount of contrast agent in the elderly group is higher than the middle-aged group ((140.05 + 82.49) vs (127.81 + /- 77.80), P < 0.001). The proportion of right coronary artery lesions in the elderly group is higher than the middle-aged group(25.2%vs18.8%). The total MACCE events and mortality in the elderly group are both higher than the middle-aged group after 30 days and 1 year (P<0.05). In the multivariate logistic regression analysis, the elderly female, the number of lesion coronary arteries, eGFR<60 were independently correlated with the mortality of elderly female ACS patients accepted PCI after 1year.
The elderly female correlated to the long-term total mortality and MACCE events in ACS patients accepted PCI independently.