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The goal of this study was to investigate the impact of gender on target lesion failure after percutaneous coronary intervention.
In the I-LOVE-IT 2 Trial, there were 858 female patients and 1879 male ones. The primary endpoint was 12-month target lesion failure (TLF), a composite of cardiac death, target vessel myocardial infarction, or clinically indicated target lesion revascularization. Secondary endpoints included 30-day TLF components, and definite/probable stent thrombosis.
At 30 days, there was no difference in TLF(3.3% vs 4.4%,P=0.144)between men and women. Similarly, TLF was comparable between men and women at 12 month(5.9% vs 7.0%,P=0.252). Multivariate analysis showed that diabetes mellitus and left Ventricular dysfunction were predictors of TLF. Gender was not associated with TLF.
No differences in TLF were observed between men and women treated with percutaneous coronary intervention.