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Paroxysmal atrial fibrillation (PAF) may re-occur despite effective radiofrequency catheter ablation (RFCA). This study was designed to discover a clinical indicator to screen the possible PAF recurrence patients after RFCA.
A total of 173 episodes of PAF on Holter recordings of PAF patients with and without structural heart disease by medical history, physical examination and routine blood chemistry profiles were enrolled into the research. Deceleration capacity (DC)and heart rate variability (HRV) parameters on Holter recordings of the study population were analyzed. An independent-sample t test was used to compare multiple variables. Differences between qualitative data were examined using non-parametric tests. The relationship between DC and HRV was tested using Spearman correlations.
DC is positively correlated to LF/HF but not to LF or HF in the PAF patients with structural heart disease. On the contrary, DC is positively correlated to LF and HF but not to LF/HF in the PAF patients without structural heart disease.
Autonomic imbalance, especially the vagal predominance, acts as a driving force behind the atrial ectopy and reentry that promote AF. Our results suggested that DC might therefore be useful to improve patient selection for target treatment strategies such as radiofrequency catheter ablation in the patient collective.