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The conventional left ventricular lead(LV lead) is unipolar or bipolar lead, they are allowed the maximal three vectors to pace. But there are ten different vectors could be acquired in the quadripolar LV lead. In this study, we investigate the application value of quadripolar left ventricular (LV) leads and their potential capability of optimizing cardiac resynchronization therapy (CRT).
Fifteen heart failure patients who received CRT device implantation with a LV quadripolar lead (St. Jude Medical) at General Hospital of Shenyang Military Region were enrolled in this study. Q–LV interval is the time interval from the onset of QRS complex to the spike of LV local electrogram. To investigate the difference of Q-LV interval between the four electrodes. we array the Q-LV in sequence in every patient and make a statistical analysis.
All of the CRT patients were diagnosed as CLBBB and the QRS duration were 167±27ms;LVEF:0.28±0.06;left ventricular end-systolic volume(LVESV): 231±82ml;6-minute-walk test: 334±92m. Every patient who underwent CRT with a LV quadripolar lead have four Q-LV data, being arranged in ascending order. Q-LV intervals of each group were 115±37ms, 125±40ms, 130±39ms and 140±43ms. The significantly statistical differences exist between the two groups of two(P<0.01).
Quadripolar left ventricular (LV) leads offer more pacing vectors compared with traditional leads, Q-LV have statistical differences between the four eletrodes, which provides potential value in CRT optimized configuration.