Author + information
- Tang Li-Hong and
- Xue Yu-Mei
Whether atrial fibrillation (AF) ablation reduces one’s stroke risk still unknown. The risk of long-term thromboembolic events (TEs) in patients with atrial fibrillation (AF) after ablation is variable and is influenced by the individual risk of stroke. Limited data are available on the predictors of it.
A total of 1227 patients with non-valvular AF who underwent catheter ablation were enrolled in the study. The clinical endpoint was occurrence of late TEs during follow-up after catheter ablation. All patients were anticoagulated with warfarin for ≥ 3 months after ablation.
Late TEs occurred in 12 of 1227 patients (0.98%). Multivariable analysis revealed that age ≥ 60 (OR 11.892; 95% CI 1.502-94.179, p=0.019) and left atrial thrombus or hypercoagulation status (OR 36.741; 95% CI 8.023-168.246, p<0.001) were independently associated with long-term TEs. In a separate model, CHA2DS2-VASc score ≥2 (OR 16.031; 95% CI 2.036-126.234, p= 0.008) and left atrial thrombus or hypercoagulation status (OR 30.813; 95% CI 6.664-142.464, p< 0.001) were significantly associated with long-term TEs.
The rate of long-term TEs for AF patients after ablation is very low. Age ≥ 60, left atrial thrombus or hypercoagulation status and CHA2DS2-VASc score ≥2 are independent predictors of such events. High-quality, randomized trial data are needed to provide more detail about it.