Author + information
- Liwei He,
- Shenrong Liu,
- Vikram Shee,
- Yanyu Chen and
- Jian Peng
Post operation Troponin elevation is implied to be related to the atrial substrate, This study aimed to investigated the relationship between left atrial diameter(LAD) and Troponin level after paroxysmal AF ablation.
97 consecutive paroxysmal AF patients undergoing radiofrequency ablation from 2015.6 to 2017.1 were recruited. All patients underwent pulmonary vein isolation alone in the index procedure, and were divided into two groups according to preablation LAD measured by echocardiography, group 1 with a LAD≤45mm(n=58), and group 2 LAD>45mm(n=39). Patients with pre-operation TnT elevation, acute coronary syndrome or acute decompensated heart failure was excluded. TnT measured 12 hours after procedure was compered between the groups.
Basal patient characteristics were similar, age (group 1 vs group 2, 56.2±9.3 vs 55.8±10.6, p=0.749), gender proportion (35/58 vs 22/39, p=0.7), hypertension(36/58 vs 20/39, p=0.292), DM(20/58 vs 16/39, p=0.77), and NYHY(I/II/III 31/23/4 vs 22/15/2, p=0.735). The groups 1 had smaller LAD(39.4±3.2 vs 50.8±3.7, p<0.001), and higher post operation TNT level(1.79±1.42 vs 1.22±1.86, p=0.026)comparing to group 2. A negative correlation existed between LAD and TnT level (r=-0.583,p=0.013).
Smaller preablation left atrial diameter is associated with higher post procedure TnT level in paroxysmal AF, which implies more preservation of healthy left atrial myocardium.