Author + information
- Lin Weidong,
- Xue Yumei,
- Fang Xianhong,
- Zhan Xianzhang,
- Liao Hongtao,
- Liu Fangzhou and
- Wu Shulin
To evaluate the predictive value of Left Atrial Diameter (LAD) on left atrial thrombus (LAT) or left atrial spontaneous echo contrast (LASEC) in Non-valvar Atrial Fibrillation Patients(NVAF) with low-moderate risk of stroke.
We enrolled 1912 patients who were diagnosed as NVAF and underwent Tran’s esophageal echocardiography (TEE) in Guangdong Cardiovascular Institute from January 2013 to December 2015. There were 604 patients with nonvalvular atrial fibrillation who were assessed as low-moderate risk of stroke (CHA2DS2-VASc score were 0 to 1). The baseline clinical characteristics, laboratory test of blood routine, echocardiographic measurements were analyzed.
Twenty patients were found LAT/LASEC on TEE. The LAD was significantly higher in LAT/LASEC patients compared with the non-LAT/LASEC patients (44.10±5.53 vs 36.21±5.52, P<0.001). ROC curve was presented by LAD, which indicated the best LAD cut-off point was 37.5 with a sensitivity of 95.0 % and a specificity of 62.7 %(Area Under Curve=0.853, 95% CI 0.793-0.914，P<0.001). Furthermore, multivariate logistic regression analysis indicated that LAD> 37.5(OR=11.98，P=0.024) could be independent risk factors for NVAF with low-moderate risk of stroke.
Elevated LAD is associated with the presence of LAT/LASEC and could be with good predictive value for NVAF with low-moderate risk of stroke.