Author + information
- Alyavi Anis Lutfullayevich1,
- Alyavi Baxrom Anisxonovich2,
- Uzokov Jamol Kamilovich1,
- Azizov Shuxrat Ismatovich2 and
- Kayumov Nodir Ulugbekovich2
Estimate the subclinical organ damage and gender differences for the cardiovascular risk stratification in hypertensive patients with metabolic syndrome.
56 hypertensive patients with metabolic syndrome were enrolled in this study (Aged 42-64 years, mean age of the patients 52±10.6 years, male=50%). Ankle-brachial index (ABI), pulse wave velocity (PWV), carotid-intima media sickness (CIMT) was assessed. Cardiovascular risk assessed according to the SCORE model. Metabolic syndrome was diagnosed by the “Harmonized definition of the MS”.
In hypertensive women with MS had lower CIMT (0.76±0.17 vs. 0.83±0.18, P<0.05), ABI (0.98±0.20 vs. 1.10±0.24, P<0.05) and higher PWV (13.0±2.95 vs. 10.82±2.50, P<0.01) than men. The cardiovascular risk was higher in hypertensive men than in women (8.25±4.9 vs. 7.12±4.0, P<0.05) with MS according to the SCORE formula.
Hypertensive women with metabolic syndrome were characterized lower CIMT, ABI and higher PWV than those counterparts. Cardiovascular risk was higher in hypertensive men than in women regardless of the presence of MS according to the SCORE.