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Our previous study has revealed that daytime napping duration was closely related to cardiovascular mortality. In this study, we investigated whether daytime nap was associated with the incidence of heart failure.
Clinical data and the information of napping habit were obtained from 618 heart failure patients (334 males and 284 females, 73.7±8.0 years) and 4424 controls (2015 males and 2409 females, 62.5±10.8 years) in a registered cohort study. All the participants completed the following question in the health questionnaire: “Do you normally take a nap during the day?” in the baseline examination. Heart failure was diagnosed with clinical manifestations, blood tests and echocardiogram. Logistic regression analysis was used to estimate the odds ratios (OR) and 95% confidence intervals (95% CI) for relationship between daytime nap and heart failure.
Daytime nappers had a higher incidence of heart failure than those not taking nap (32.7% vs. 10.2%; p<0.001). After multivariate logistic regression analysis, daytime nap (OR 1.321; 95%CI 1.072-1.628; p=0.009), age (OR 1.114; 95%CI 1.101-1.127; p<0.001), hypertension (OR 2.345; 95%CI 1.912-2.875; p<0.001), high density lipoprotein (OR 0.988; 95%CI 0.980-0.996; p=0.003) and BMI (OR 1.049; 95%CI 1.028-1.070; p<0.001) were associated with the incident heart failure.
Our study suggested that daytime nap might be independently associated with heart failure. However, the mechanism remains to be further investigated in the future study.