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Analysis sonograms feature of cardiovascular malformation and its associated anomalies in fetus with right atrial isomerism.
The sonograms and autopsy data of 3 cases found in 256 pregnant women and 676 cases found in literature with right atrial isomerism which confirmed by angiocardiography, autopsy, and surgical operation were analyzed retrospectively.
In our 3 cases, the stomach and gallbladder were all located on the right side, asplenia in 2 cases, and the other was located in the right side. They were trilobites lung (asymmetric),and both sides were the right auricle(asymmetric). Associated anomalies included right valve atresia, single ventricle, single atrium, complete atrioventricular atrioventricular septal defect, double outlet of right ventricular, right aortic arch, pulmonary artery stenosis, total anomalous pulmonary venous connections, etc.
The main cardiovascular abnormalities included anomalous pulmonary venous connections(57.6%), single ventricle(64.8%), single atrium (21.5%), endocardial cushion defect (37.8%), double superior vena cava (24.9%), double outlet of right ventricular (24.2%), pulmonary artery stenosis (33.9%), pulmonary atresia(19.7%), VSD, right aortic arch, PDA, and left superior vena cava, etc.
In 284 cases, The median of liver (97%), asplenia (91.1%), abdominal aorta and inferior vena cava located in the same side of spine (93.6%), bilateral trilobites lung (87.9%), bilateral right bronchial (100%), were the main abnormalities Outside the heart.
Right atrial isomerism was combined complex cardiac anomalies, short-term and long-term prognosis were not optimistic. They always accompanied the median of liver, asplenia, abdominal aorta and inferior vena cava located in the same side of spine, anomalous pulmonary venous connection, etc. Prenatal ultrasound was effective method for diagnosis of the fetus with right atrial isomerism.