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To investigate the association between Hamilton Depression Scale-24 (HAMD-24) score and ejection fraction in patients with type 2 diabetes mellitus (T2DM)
195 patients with T2DM were enrolled in first cardiology department in Shaanxi Provincial People's Hospital. Hamilton Depression Scale-24 (HAMD-24) score were documented, the demographic, laboratory, ejection fraction (EF) data via ultrasound were also collected. The Pearson correlation was performed to detect the correlation between the HAMD-24 score and EF values. The multiple linear regression models were constructed to evaluate the association between the HAMD-24 score and EF values after adjustment of confounding factors.
104 patients (57.4%) were defined as depression using HAMD-24 score. Smoking index, duration of T2DM, triglyceride, percentage of female gender and insulin use in patients with depression were significantly higher than those in patients without depression (P<0.05). The EF values in patients with depression were significantly lower than those in patients without depression (P<0.05). The Pearson correlation showed that HAMD-24 score was negatively correlated with EF values (r=-0.317, P=0.003). With multiple linear regression analysis, the EF values were significantly associated with HAMD-24 score after the adjustment of smoking index, duration of T2DM and triglyceride (β =-0.423, P<0.001).
EF values were associated with depression in patients with type 2 diabetes mellitus