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Sleep duration is associated with the incidence of stroke. However, the relationship between individual daytime napping duration and stroke remains unknown.
The study population of 4993 individuals were extracted from a multi-center cohort study (ClinicalTrials.gov Identifier: NCT00005275). Neurological examination, CT scans,MRI scans, or arteriography were used for the diagnosis of stroke. All the participants were divided into stroke group and control group at the end of the follow-up visit. The napping habit was recorded based on questionnaire when interviewing patients upon their recruitment. Descriptive statistics are presented as percentages for discrete variables and as means (standard deviation) for continuous variables. Multivariate logistic regression was used to examine the relationship between napping duration and stroke.
In our study, a total of 66 patients with napping habit (23.3%) were found in stroke group, while 670 nappers (14.2%) were observed in control group. After analysis of multivariate logistic regression, it suggested that daytime napping ≥15min (OR 1.585; 95%CI 1.169-2.149; p=0.003), BMI (OR 1.044; 95%CI 1.016-1.072; p=0.002) and hypertension (OR 3.010; 95%CI 2.308-3.926; p<0.001) might contribute to the stroke.
Daytime napping habit may serve as one of the independent risk factors for stroke especially when the duration lasts longer than 15 mins. Therefore, personalized life management in daytime napping is worth further evaluation in clinical trials in patients with stroke.