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To observe the effect of rivaroxaban combination with aspirin on prevention of deep venous thrombosis in elderly patients with hip fracture.
120 cases were randomly divided into observation group and control group, and the control group were divided into two groups (group 1 and group 2), 40 cases in each group, the observation group with rivaroxaban combined with aspirin, The control group 1,control group 2 respectively by rivaroxaban and aspirin, And then comparing the 3 groups of patients with DVT incidence and preoperative, blood coagulation function, D-dimer changes.
In the observation group, the incidence rate of DVT lower than that of control group 1 and control group 2,while the incidence rate of DVT control group 1 lower than the control group 2,the differences were statistically significant (P<0.05).all of the patients with postoperative hemoglobin platelets were lower than those before operation, the differences were statistically significant (P<0.01),no statistical significance between the two groups (P>0.05).all of the patients show no statistically significant on blood coagulation function, D-D (P>0.05).
There was very important to prevent DVT of hip fracture in elderly patients, rivaroxaban combined with aspirin may effectively prevent DVT,which is worthy of clinical application.