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Piezoelectric pressure measurements with multiple sensors might improve efficiency and accuracy in collecting arterial pressure waveforms for measurement of pulse wave velocity. In the present study, we validated a prototype based on piezoelectric sensor-array (Philips) against the clinically validated and widely used Complior device (Artech).
We recruited 33 patients with a wide distribution of blood pressure measured with validated sphygmomanometer. PWV was measured sequentially with the Complior device (4 times) and the Philips prototype (3 times). With the 99 paired PWV values, we investigated agreement between the Philips prototype and Complior device by Pearson’s correlation analysis and Bland-Altman plot. We also performed analysis on determinants of PWV measured with both devices, and on reproducibility of both devices.
The correlation coefficient for PWV measured with the Philips prototype and the Complior device was 0.918(P<0.0001). Compared with the Complior device, the Philips prototype slightly overestimated PWV by 0.238(±2 standard deviations, ±1.907) m/s, especially when PWV was high. The correlation coefficient between the difference and the average of the Philips and Complior measurements was 0.212 (P=0.035). Nonetheless, they had similar determinants. Age, mean arterial pressure and gender altogether explained 84.3% and 93.6% of the variance of PWV values measured with the Philips prototype and Complior device, respectively. When the two extreme of the 3 PWV values measured with the Philips and Complior device were investigated, the reproducibility coefficients were 8.26% and 3.26%, respectively.
Compared with Complior device, Philips prototype had similar accuracy, determinants and reproducibility in measuring PWV.