Author + information
- Longbing Ren1,2,
- Yongtao Zheng1,2,
- Yijun Gu1,2,
- Yusheng He3,
- Bo Jiang1,2,
- Wei Wang1,2,
- Chunyan Wu1,2,
- Han Yu1,2,
- Jie Zhang1,2,
- Lijuan Zhang1,2 and
- Jue Li1,2
- 1Shanghai East Hospital, Key Laboratory of Arrhythmias, Ministry of Education, Tongji University School of Medicine, Tongji University, Shanghai, China
- 2Institute of Clinical Epidemiology and Evidence - based medicine, Tongji University School of Medicine, Shanghai, P.R. China
- 3Department of Neurology, Tongji Hospital, Tongji University, Shanghai, China
To investigate the prevalence of cognitive impairment and its risk factors among the elderly population in Shanghai, China.
A community-based, cross-sectional study was conducted among 480 participants (≥80 years old) from May 2016 to June 2016. Cognitive function was measured according to the questionnaires of Mini-Mental Status Examination (MMSE). Pearson’s chi-squared test and binary logistic regression were used to analyze the association between potential risk factors and cognitive impairment. Multiple correspondence analysis models were used to evaluate the potential and association for every module of cognitive function.
Of the 480 participants, 144 (30%) were associated with cognitive impairment. Female and solitary were independent risk factors, whereas income of more than 2000 Yuan, body mass index (BMI)>24, more than 60 min physical activity, use of antihypertensive drugs and lipid lowering drugs (LLD) were protective factors for cognitive impairment. Moreover, recall or attention and calculation may be related to income and use of LLD.
The prevalence of CI among the elderly population aged 80 years and older in our study was found to be approximately 30%. The main cognitive performances associated with CI may be the decreased abilities of Recall or Attention and Calculation. Risk factors for CI in an elderly population include: higher income, more than 60 min physical activity, BMI<24, use of antihypertensive drugs and LLD. Protective factors for CI in an elderly population include: more than 60 min physical activity, and rational use antihypertensive drugs and LLD.