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Social support is generally identified to associated with health-related quality of life(HRQoL) and prognosis among patients with coronary heart disease(CHD).Few study described the changes of social support during follow-up. We evaluated the changes of social support at 12 months and taken anxiety into account for health outcomes of acute coronary syndrome(ACS) patients in mainland China.
778 patients with ACS were consecutively enrolled in the study within 7 days after admission from 5 hospitals in Beijing China.Social support(ENRICHD Social Support Inventory),health status(Short Form-12 physical and mental component scores),anxiety(Anxiety Disorder-7 scale),depressive symptoms(Patients Health Questionnaire),and angina-related quality of life(Seattle Angina Questionnaire) were investigated at baseline and 12 months.Mortality,recurrent angina,non-fatal myocardial infarction and re-hospitalization were observed during 12 months follow-up.
Patients with low social support at baseline presented more anxiety,worse mental functioning and angina-related quality of life than patients with moderate/high social support(all P<0.05).Mortality and non-fatal myocardial infarction were low in the overall cohort and not differ by social support(P>0.05).Whereas,patients with low social support at baseline were at greater risk of a recurrent angina(HR1.16,95%CI1.06-2.62,P<0.05) and rehospitalization(HR2.16,95%CI1.16-4.05,P<0.05) than those who had moderate/high social support over follow-up period.In average social support and health-related quality of life had been significantly improved regardless of baseline social support level at 12 month(all P<0.01).
Low social support was a predictor for worse health outcomes and recurrent angina,re-admission among Chinese ACS patients.Social support level experienced an improvement at 12 months post-ACS.Future studies is needed to figure out the mechanism of social support change and to develop the specific intervention for social support.