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To investigate the relationship between corpuscular volume and ACS severity and short-term prognosis, and provide a new diagnostic theory for clinical practices.
A total of 168 patients (aged 20-90 years, 42.24% male, 54.76% female) were enrolled in this study, including 50 patients with ACS, and 118 patients without ACS as control. The group of ACS contained 22 patients with UA and 15 patients with STEMI, and 13 patients with NSTEMI. All of them had TMIM and then GRACE score was calculated. The relation of CV and GRACE score and the cumulative value of coronary lesions were analyzed. All detailed records of general data and results of the examinations were recorded clearly. Every ACS patient had been interviewed by telephone after one month to evaluate adverse cardiovascular events during the one month, such as angina pectorals grade of CCS raised up at least of 1 grade, recurrence of myocardial infarction, onset of heart failure, cardiac death and so on. According to the thresholds of CV shown by ROC curve analysis, the patients with ACS were divided into high-levels group, middle-levels group and low-levels group. And the incidence of short-term adverse cardiovascular events was compared between the two groups.
1. The elderly patients with hypertension, diabetes mellitus and hyperlipidemia were more likely to suffer from ACS. The blood volume of erythrocytes in ACS patients was significantly higher than that in UA patients. The erythrocyte volume of STEMI and NSTEMI was higher than that of UA patients.
2. TIMI, GRACE score showed ACS patients with coronary artery disease severity increased significantly.
3. The volume of erythrocyte is associated with the occurrence of cardiovascular adverse events in ACS patients. The elevated erythrocyte volume is one of the predictors of adverse events of ACS patients.
4. The erythrocyte volume was significantly correlated with gender, TIMI and troponin, suggesting that elevated erythrocyte levels in patients with ACS may be related to their physiological status and impaired cardiac function.
In summary, we measured red blood cell volume and severity of ACS patients and recent prognosis evaluation and other aspects of the correlation, further confirmed ACS patients with abnormal red blood cell volume increased, and its severity may be related to coronary artery disease, Their physiological condition and impaired cardiac function, which provides a theoretical basis for the diagnosis of ACS patients and the prediction of adverse prognosis.