Author + information
Previous studies have presented conflicting results on the relationship between siesta and coronary artery disease. This case-control study was performed to evaluate the association of daytime napping duration with angina retrospectively.
In this hospital-based case-control study, 2200 angina patients (57.7% male, 64.0±7.8 years) and 2200 age-and sex-matched controls (59.1 male, 64.6±8.3 years) were recruited from a multi-center cohort study. The diagnosis of angina pectoris is based on symptoms and other examinations such as electrocardiogram, stress echocardiography, 24-hour ambulatory electrocardiogram or coronary angiography. The daytime napping status was based on questionnaires taken in the baseline examination. Multivariate logistic regression analysis was used to explore the association of napping duration with angina.
Patients with angina (619 patients, 28.1%) were prone to have more daytime naps than control subjects (450 patients, 20.4%). After adjustment for potential confounding factors, multivariate logistic regression analysis showed that daytime napping duration longer than 45mins (OR 0.692; 95% CI 0.504-0.952; p=0.024) and smoking (OR 1.203; 95%CI 1.069-1.354; p=0.002) were associated with angina.
These results suggest that longer daytime nap may reduce the risk of angina. However, further clinical trials are needed to confirm our findings and investigate the underlying mechanisms.