Author + information
- 1North Shore University Hospital- Northwell Health, Manhasset, New York, United States
- 2Northshore University Hospital, Manhasset, New York, United States
- 3Rutgers New Jersey Medical School, Newark, New Jersey, United States
- 4Cardiovascular Research Foundation, New York, New York, United States
- 5New York Methodist Hospital, Brooklyn, New York, United States
- 6Hofstra Northwell School of Medicine , New York, Manhasset, New York, United States
Aortic Valve Stenosis (AS) is common in the elderly. Transcatheter Aortic Valve Replacement (TAVR) in such patients is being increasingly performed. This study sought to assess in-hospital outcome differences between octogenarians and nonagenarians undergoing TAVR with severe AS.
The study population was derived from the National Inpatient Sample (NIS) for the years 2012-2014 using ICD-9 CM procedure codes 35.05 and 35.06 for TAVR. Patients below 80 years of age were excluded. After performing propensity score matching (1:2), in-hospital outcomes were compared in matched cohorts using appropriate statistical tests.
There were 2326 patients in the octogenarian and 1163 patients in the nonagenarian group. Compared to octogenarian group patients, nonagenarian group had higher in-hospital mortality, our primary outcome. All secondary outcomes were higher with nonagenarians. No difference in their length of stay was noticed. Median cost was slightly higher with nonagenarian patient’s admission for TAVR.
In-hospital mortality and secondary outcomes were higher in nonagenarians, but no difference in length of stay was noted between the groups. Our study showed that TAVR is safe and effective in patients above 80 years of age and it improves the quality of life. However, very old patients may need closer monitoring to further avoid in-hospital mortality and morbidities.
STRUCTURAL: Valvular Disease: Aortic