Author + information
- Piotr Buszman1,
- Bartlomiej Orlik1,
- Mateusz Kachel1,
- Aleksandra Kolarczyk-Haczyk2,
- Łukasz Konarski1,
- Katarzyna Czerwińska-Jelonkiewicz1,
- Adam Janas3,
- Aleksandra Chorianopoulos4,
- Aleksander Zurakowski1,
- Paweł Buszman1 and
- Krzysztof Milewski1
- 1Center for Cardiovascular Research and Development, American Heart of Poland, Katowice, Poland
- 2San Antonio Endovascular and Heart Institute, San Antonio, Texas, United States
- 3Center of Cardiovascular Research and Development, American Heart of Poland, Katowice, Poland
- 4Center for Cardiovascular Research and Development, Katowice, Poland
Long coronary lesions are challenging subset in which two overlapping drug eluting stents are usually implanted. Recently very long sirolimus eluting stents (30-55 mm) have been introduced as an alternative solution. In current study we compared long term outcomes after implantation of two overlapping everolimus eluting stents (EES, Xience, Abbot, USA) vs. one very long sirolimus eluting stent (30-55 mm SES, BioMime Long, Meril Lifesciences, India).
This is a multicentre, prospective, hospital information system based registry of 377 consecutive symptomatic patients with occlusive, single and long coronary lesion (>30 mm). Patients both with stable angina and acute coronary syndromes who underwent elective PCI using exclusively two EES implantation (n=254) or one long SES (n=123) were included. Follow-up was collected at 2 years.
Follow-up was collected from 90% of patients. At baseline, patients in long SES group were slightly older (68.8±9 vs. 65.1±10 y.o.; p<0.01) and more often presented with unstable angina (48.8 vs. 33.5%; p<0.01). At follow-up the incidence of major adverse cardiovascular events (28.7 vs. 30.0%; p<0.82), death (8 vs. 13%; p=0.16), any repeated revascularization (18.5 vs. 19.4%; p=0.31), target vessel revascularization (6.6% vs. 5.5%; p=0.7) and myocardial infarction (7.0 vs. 5.4%; p=0.6) was comparable between two EES and one long SES consecutively. There were no definite or probable stent thrombosis. These results were sustained after selection of 123 well matched pairs with propensity score.
Based upon this hypothesis generating registry, implantation of one long SES is feasible and is associated with similar long term clinical outcomes when compared to two overlapping EES.
CORONARY: Stents: Drug-Eluting