Author + information
- Wojciech Wanha1,
- Maksymilian Mielczarek2,
- Grzegorz Smolka1,
- Tomasz Roleder3,
- Miłosz Jaguszewski4,
- Michal Chmielecki4,
- Stanislaw Bartus5,
- Adam Sukiennik6,
- Jacek Kubica6,
- Andrzej Lekston7,
- Michal Hawranek7,
- Krzysztof Reczuch8,
- Andrzej Ochala1 and
- Wojtek Wojakowski1
- 1Third Department of Cardiology and Structural Heart Diseases, Medical University of Silesia, Katowice, Poland
- 2Medical University of Gdansk, Gdansk, Poland
- 3Third Division of Cardiology, Medical University of Silesia, Katowice, Poland
- 4Department of Cardiology, Medical University of Gdańsk, Gdańsk, Poland
- 5Jagiellonian University, Krakow, Poland
- 6Department of Cardiology Nicolaus Copernicus University, Collegium Medicum, Bydgoszcz, Poland
- 73rd Department of Cardiology, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia, Katowice, Poland
- 8Department of Cardiology, Medical University of Wrocław, Wroclaw, Poland
There paucity of real-life data on left main (LM) therapy with self-expandable DES. The following Stentys Left Main registry aimed to assess clinical outcomes of LM percutaneous coronary intervention (PCI) using such self-expandable platform (Stentys).
A multicenter registry consists of 154 consecutive patients treated with Stentys implanted to LM. Major adverse cardiac and cerebral events (MACCE) such as composite of death, myocardial infarction (MI) and stroke were recorded at 30-days and 12-months.
Patients’ mean age was 69±10.5 years. Acute coronary syndrome was diagnosed in 40 (26.5%) cases including NSTE-ACS (n=28, 18.1%) and STEMI (n=12, 7.8%). Median EuroSCORE II was 2.2% (IQR 1.0-4.5). Prior CABG were performed in 40 (25.9%) patients. Mean LVEF was 46.0±11,9%. Distal LM bifurcation lesions were present in 152 (98.7%) patients [Medina: 1,1,1 (n=59, 38.3%), 1-1-0 (n=62, 40.2%), 1-0-1 (n=16, 10.4%), 1-0-0 (n=17, 11.1%)]. There was a significant difference between proximal and distal reference diameter of the lesions [4.0 (IQR 3.9-4.1) vs. 2.9 (IQR 2.8-3.0), p<0.001]. Stentys DES was implanted in the sequence LM to LAD in 107 (69.4%) cases. Stentys strut disconnection for SB access were done in 94 (61.2%) patients, because of angiographically significant stenosis of SB. Final kissing balloon inflation was performed in 25 (16%) cases. Six patients required ventricular assist devices during procedure. One patient had an acute stent thrombosis (ST) and one patient had late ST post PCI, there were 7 (4.5%) cardiac death, 2 (1.2%) target lesion revascularization (TLR), 3 (1.9%) MI and 9 (5.8%) MACCE during 30 days follow-up. At 12-month follow-up there were 9 (5.8%) cardiac death, 9 (5.8%) TLR, 7 (4.5%) MI and 19 (12.3%) MACCE. In two cases, TLR was the cause of MI.
The real-life multicenter registry showed that the use of Stentys DES self-expanding coronary stent is associated with acceptable short and midterm outcomes in all-comer population of patients including ACS with significant LM stenosis.
CORONARY: PCI Outcomes