Type of Atrial Fibrillation and Outcomes in Patients With Heart Failure and Reduced Ejection Fraction
Ulrik M. Mogensen, Pardeep S. Jhund, William T. Abraham, Akshay S. Desai, Kenneth Dickstein, Milton Packer, Jean L. Rouleau, Scott D. Solomon, Karl Swedberg, Michael R. Zile, Lars Køber, John J.V. McMurray and on behalf of the PARADIGM-HF and ATMOSPHERE Investigators and Committees
Type of AF at Randomization Compared With Patients Without AF: HRs of Outcomes
Hazard ratios (HRs) of outcomes according to type of atrial fibrillation (AF) using no AF as reference. HRs with 95% confidence intervals were calculated using cause-specific Cox models, adjusted for age, sex, region, race, New York Heart Association functional class, ejection fraction, heart rate, systolic blood pressure, estimated glomerular filtration rate, diabetes, body mass index, time since HF diagnosis, history of HF hospitalization, history of myocardial infarction, history of stroke, log N-terminal pro–B-type natriuretic peptide, and randomized treatment (enalapril, sacubitril/valsartan, aliskiren, or combination). The p values are for difference between paroxysmal and persistent or permanent AF. CV = cardiovascular.