Author + information
- Wasawat Vutthikraivit,
- Saranapoom Klomjit,
- Pattara Rattanawong,
- Pakpoom Tantrachoti,
- Pavida Pachariyanon,
- Awapa Prombandankul,
- Possawat Vutthikraivit and
- Mohammad Ansari
Recent studies suggested that chronic total occlusion of the coronary artery increased risk of ventricular arrhythmia (VA) and all-cause mortality in ischemic cardiomyopathy (ICM) patient who underwent implantable cardiac defibrillator (ICD) implantation. We aim to determine adverse events in this population.
We comprehensively searched the databases of MEDLINE and EMBASE from inception to September 2017. The studies that compared adverse events (appropriate shock and all-cause mortality) between patients with and without CTO of the coronary artery who had ICD were included for meta-analysis.
Five studies from 2015 to 2017 were included in this meta-analysis involving 1,095 subjects (505 CTO and 590 non-CTO). The presence of CTO was significantly associated with increased risk of appropriated shock (pooled risk ratio =1.60, 95% confidence interval: 1.29-1.99, p<0.001, I2=73.2%) and all-cause mortality (pooled risk ratio=1.65, 95 % confidence interval: 1.22-2.24, p=0.008, I2=35.1%) in ICD implanted ICM patients (figure 1.1 and 1.2).
Presence of CTO of the coronary artery increased risk of appropriate shock following VA and all-cause mortality in ICD implanted ICM patients up to 60 and 71 percent, respectively. Our study suggested that CTO is an independent predictor of unfavorable outcome and must be addressed in ICM patients with ICD.
Poster Hall, Hall A/B
Saturday, March 10, 2018, 10:00 a.m.-10:45 a.m.
Session Title: Interventional Cardiology: Imaging, Short-Term and Long-Term Outcomes in CTO PCI
Abstract Category: 20. Interventional Cardiology: Coronary Intervention: CTO
Presentation Number: 1113-254
- 2018 American College of Cardiology Foundation