Author + information
- Bipin Sunkara,
- Yumeng Li,
- Konstantinos Siontis,
- Miki Yokokawa,
- Rakesh Latchamsetty,
- Hamid Ghanbari,
- Thomas C. Crawford,
- Krit Jongnarangsin,
- Frank Pelosi,
- Aman Chugh,
- Fred Morady and
- Hakan Oral
It is not clear whether maintenance of sinus rhythm after catheter ablation (CA) of atrial fibrillation (AF) is associated with an improvement in activity levels and exercise tolerance and a subsequent decrease in body weight.
We included 987 patients (mean age=61±10 years) with paroxysmal (n=605) or persistent AF (n=382) who underwent first CA (2010-2014). During a mean follow-up of 9±5 months after CA, rhythm status and body weight were assessed during 11±13 clinic visits per patient. Patient-level longitudinal mixed effect regression models examined changes in body weight after CA, and whether this trajectory varied by recurrence status.
A total of 476 (48.2%) patients experienced recurrent atrial arrhythmias after the CA. Among patients who remained in sinus rhythm, there was a non-significant trend towards weight loss after CA (0.05 kg/month; P = 0.170). Among patients who had recurrence of atrial arrhythmias, there was significant weight loss before the recurrence (0.128 kg/month; P < 0.001), but subsequently body weight increased by 0.17 kg/month after the recurrence (P<0.001, Figure 1). The relationship between rhythm status and body weight was independent of age (P = 0.426), gender (P = 0.550), sleep apnea (P = 0.134) or diabetes mellitus (P = 0.429).
Maintenance of sinus rhythm after CA of AF may be associated with a decrease in body weight, likely due to an improvement in activity and exercise tolerance.
Poster Hall, Hall A/B
Saturday, March 10, 2018, 10:00 a.m.-10:45 a.m.
Session Title: Newer Insights Into Atrial Fibrillation
Abstract Category: 04. Arrhythmias and Clinical EP: Basic
Presentation Number: 1102-020
- 2018 American College of Cardiology Foundation