Author + information
- Courtney McCracken,
- Logan Spector,
- Jessica Knight,
- Jeremiah Menk,
- James Moller and
- Lazaros Kochilas
Children surviving surgical procedures for congenital heart disease (CHD) continue to be at risk for increased mortality compared with the general population, but the specific causes of death (COD) in this population are not well described. This study presents the underlying COD in a large US-cohort of children operated at <21y of age for CHD.
We linked US-born patients operated 1982- 2003 in a US-center member of the Pediatric Cardiac Care Consortium (PCCC) with the National Death Index (NDI) through 2014. Data provided by NDI included International Classification of Disease codes for underlying COD and associated morbidities/events contributing to death. Patients with known chromosomal abnormalities indicated in PCCC were excluded.
Among 31,132 patients surviving their initial congenital heart surgery there were 2,527 deaths (8.1%) over a max follow up period of 33 years (median 18.1; IQR:14.5 -22.2). Median age at death was 1.8 year (IQR: 0.5-12.8). COD varied by severity and type of CHD but, overall, 83.2% of late mortality was associated with CHD or another cardiovascular condition (Figure 1A). As patients aged, the proportion of deaths caused by accidents/injury, diseases of the respiratory system and cancer increased (Figure 1B).
Patients operated for even the mildest forms of CHD are at high risk for premature cardiovascular death directly or indirectly related to their underlying CHD warranting continued monitoring to address associated morbidities.
Poster Hall, Hall A/B
Sunday, March 11, 2018, 9:45 a.m.-10:30 a.m.
Session Title: Caring For Patients In and Out of the Hospital
Abstract Category: 10. Congenital Heart Disease: Pediatric
Presentation Number: 1208-369
- 2018 American College of Cardiology Foundation