Author + information
- Georgios Benetos,
- Konstantinos Toutouzas,
- Georgios Oikonomou,
- Iosif Koutagiar,
- Fotini Mitropoulou,
- Nikolaos Barampoutis,
- Periklis Davlouros,
- Andreas Synetos,
- Elias Siores and
- Dimitris Tousoulis
Inflammation is a recognized characteristic of vulnerable atherosclerotic plaque. Microwave radiometry (MWR) allows the noninvasive assessment of the internal temperature of carotid arteries. In the present study we investigated whether patients with documented coronary artery disease (CAD) and increased carotid inflammation suffer more common cardiovascular events.
Consecutive patients with significant CAD from three tertiary centers were included in the study. Max carotid plaque thickness was assessed in all carotids by ultrasound. ΔT by MWR was assigned as the temperature difference (maximal minus minimum) along the carotid artery. ΔT ≥0.90°C was assigned as high ΔT. Major cardiovascular event (MACE) was defined as death, stroke, myocardial infarction or revascularization. All patients were followed-up clinically for two years.
In total 249 patients were included in the study. High ΔT temperatures bilaterally were measured in 38 patients (15.3%). MACE was 38.7% in the group with bilateral high ΔT and 11.9% in non-high ΔT group (P<0.001). In Kaplan-Meier plots patients with bilateral high ΔT showed higher event rate (log-rank P<0.001, figure panel A), death (log-rank p=0.008, figure panel B), and myocardial infarction (log-rank p=0.01, figure panel C)
Bilateral carotid inflammation predicts high two-year cardiovascular event rates, including death and myocardial infarction.
Poster Hall, Hall A/B
Saturday, March 10, 2018, 3:45 p.m.-4:30 p.m.
Session Title: Managing Patients With Stable Ischemic Heart Disease: A Multitude of Things to Consider
Abstract Category: 02. Acute and Stable Ischemic Heart Disease: Clinical
Presentation Number: 1171-443
- 2018 American College of Cardiology Foundation