Author + information
- Received December 30, 2017
- Revision received February 2, 2018
- Accepted February 7, 2018
- Published online April 2, 2018.
- aDepartment of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee
- bDepartment of Pediatrics, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee
- cDepartment of Health Policy, Vanderbilt University, Nashville, Tennessee
- ↵∗Address for correspondence:
Dr. H. Keipp Talbot, Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, 1161 21st Avenue South, A2200 MCN, Nashville, Tennessee 37232.
Respiratory syncytial virus (RSV) is historically known for causing respiratory illness in young children, but the appreciation of its impact on older adults is growing. Studies have shown that hospitalization for respiratory illness due to RSV is complicated by cardiovascular events in 14% to 22% of adult patients, including worsening congestive heart failure, acute coronary syndrome, and arrhythmias. Additionally, underlying cardiovascular disease is associated with hospitalization in 45% to 63% of adults with confirmed RSV. In summary, patients with cardiopulmonary disease have higher rates of health care utilization for RSV-related illness and worse outcomes. Patients with cardiovascular disease likely represent an important target population for the rapidly developing field of RSV vaccines.
Dr. Talbot has received research funding from Sanofi Pasteur, MedImmune, and Gilead; and served as a safety advisor for Sequirius and VaxInnate. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.
- Received December 30, 2017.
- Revision received February 2, 2018.
- Accepted February 7, 2018.
- 2018 American College of Cardiology Foundation
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