Author + information
- Received January 23, 2018
- Revision received July 27, 2018
- Accepted July 30, 2018
- Published online October 1, 2018.
- Peter E.H. Schwarz, MD, MBAa,b,c,∗∗ (, )
- Patrick Timpel, MSc, DiplSozarb/Sozpäda,∗∗∗ (, )
- Lorenz Harst, MAd,∗,
- Colin J. Greaves, PhD C Psychole,
- Mohammed K. Ali, MD, MSc, MBAf,
- Jeffrey Lambert, BSc, MSc, PhDg,
- Mary Beth Weber, PhD, MPH, BScf,
- Mohamad M. Almedawar, MSch,i,∗ and
- Henning Morawietz, PhDi,∗
- aDepartment for Prevention and Care of Diabetes, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
- bPaul Langerhans Institute Dresden of the Helmholtz Center Munich at University Hospital and Faculty of Medicine, Technische Universität Dresden, Dresden, Germany
- cGerman Center for Diabetes Research (DZD e.V.), Neuherberg, Germany
- dResearch Association Public Health Saxony/Center for Evidence-Based Healthcare, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
- eSchool for Sport, Exercise and Rehabilitation, University of Birmingham, Birmingham, United Kingdom
- fHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia
- gThe Institute of Health Research, Primary Care, University of Exeter Medical School, Exeter, United Kingdom
- hDresden International Graduate School for Biomedicine and Bioengineering, Technische Universität Dresden, Dresden, Germany
- iDivision of Vascular Endothelium and Microcirculation, Department of Medicine III, University Hospital and Faculty of Medicine, Technische Universität Dresden, Dresden, Germany
- ↵∗Address for correspondence:
Dr. Peter E.H. Schwarz, Department for Prevention and Care of Diabetes, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
- ↵∗∗Mr. Patrick Timpel, Department for Prevention and Care of Diabetes. Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
The primary objective of this study was to analyze the most up-to-date evidence regarding whether and how blood sugar regulation influences cardiovascular health promotion and disease prevention by carrying out an umbrella review. Three separate, systematic literature searches identified 2,343 papers in total. Overall, 44 studies were included for data extraction and analysis. The included systematic reviews and meta-analyses published between January 1, 2016, and December 31, 2017, were of good to very good quality (median Overview Quality Assessment Questionnaire score = 17). Identified evidence suggests that cardiovascular disease (CVD) prevention services should consider regulation of blood glucose as a key target for intervention. Furthermore, the recommendations for effective intervention and service development/training described here for prevention of CVD should be adopted into evidence-based practice guidelines. Multidisciplinary teams should be formed to deliver multicomponent interventions in community-based settings. There may be substantial opportunities for integrating CVD and diabetes prevention services.
↵∗ Dr. Schwarz, Timpel, Harst, Almedawar, and Morawietz contributed equally to this work. The authors have reported that they have no relationships relevant to the contents of this paper to disclose.
- Received January 23, 2018.
- Revision received July 27, 2018.
- Accepted July 30, 2018.
- 2018 American College of Cardiology Foundation
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