Author + information
- Mohinder R. Vindhyal,
- Paul Ndunda,
- Cyrus Munguti,
- Shravani Vindhyal and
- Hayrettin Okut
Since the introduction of E-Cigarettes(E-cigs) in 2007, their sales have almost increased by 14 - fold in the last decade. In the US, the E-Cig users increased to 3.8% of the adult population of which 16% are current smokers and 22% are former smokers. E-cigs have been advertised as a safer alternative to smoking. However, E-cig use, like smoking, delivers ultra-small aerosol particles which may be associated with cardiovascular disease.
This study is a cross-sectional analysis of the National Health Interview Survey (NHIS) data of 2014 (n= 36,697), 2016 (n=33,028) and 2017(n= 26,742). The following outcomes were analyzed for e-cig users vs. non-users and smoker's vs. non-smokers: myocardial infarction, hypertension, diabetes, depression/anxiety/emotional problems, circulatory problems, and stroke. For the outcomes, multiple logistic regression model was conducted to determine the covariate-adjusted odds ratio as well as to achieve the most appropriate p-value for the effects in the model. Variables such as age, BMI and sex were considered as covariates in multiple logistic regression models using SAS 9.4 software.
Compared with non-E-Cig-users, E-cigarette users had a lower mean age (32.9 vs 40.4 years) and similar BMI (28.1 vs 28.07). In multiple logistic regression analysis, E-Cig users had higher odds of having myocardial infarction [OR - 1.558, 95% CI (1.447, 1.678), P <0.0001], stroke [OR - 1.297, 95% CI (1.201, 1.400), P <0.0001], depression/anxiety/emotional problems [OR- 2.200, 95% CI (2.063, 2.347), P<0.0001] and circulatory problems [OR - 1.436, 95% CI (1.251, 1.648), P <0.0001]. E-cig users had lower odds of having diabetes. There was no significant difference between the two groups on the odds of hypertension [OR - 0.971, 95% CI (0.942, 1.001), P = 0.059].
E-cig users have higher odds of myocardial infarction, stroke, depression/anxiety/emotional problems, circulatory problems and lower risk of hypertension and diabetes compared to non-E-cigarette users. However, there is a need for cohort studies to establish the causation linkage for the cardiovascular outcomes described above.
Monday, March 18, 2019, 9:04 a.m.-9:14 a.m.
Session Title: Highlighted Original Research: Prevention and the Year in Review
Abstract Category: 32. Prevention: Clinical
Presentation Number: 911-12
- 2019 American College of Cardiology Foundation