A Percutaneous Carotid Coil Filter for Stroke Prevention in Atrial Fibrillation
The permanent carotid coil filter is implanted bilaterally in the common carotid arteries, by direct skin puncture in the neck atop the common carotid arteries using a 24-gauge needle inserter. The filter is configured to capture emboli that exceed 1.4 mm in size originating below the neck, including the heart or aorta, thereby protecting the brain against ischemic stroke of (cardio)embolic source. In the first-in-human CAPTURE clinical trial, implantation of the coil filter was feasible with high success rates, safe, and effective in capturing thromboemboli. Furthermore, these captured thromboemboli resolved over time, at least in part due to the action of endogenous thrombolytic enzymes. CHA2DS2-VASc = Congestive heart failure, Hypertension, Age 75 years, Diabetes, Stroke/transient ischemic attack, Vascular disease, Age 65 to 74 years, Sex category.