Author + information
- Received August 6, 1985
- Revision received January 10, 1986
- Accepted January 29, 1986
- Published online July 1, 1986.
- Hasan Garan, MD, FACC*,1,3,
- Khiem Nguyen, MD1,
- Brian McGovern, MB1,
- Mortimer Buckley, MD, FACC1 and
- Jeremy N. Ruskin, MD, FACC1,2
- ↵*Address for reprints: Hasan Garan, MD, Cardiac Unit, Massachusetts General Hospital, Boston, Massachusetts 02114.
Thirty-six patients underwent ventricular aneurysmectomy and electrophysiologically directed endocardial resection for treatment of recurrent ventricular tachycardia refractory to antiarrhythmic drug therapy. The surgical mortality rate was 17% and all 30 patients discharged from the hospital were alive at the end of the follow-up period (range 6 to 54 months), yielding a cumulative projected survival rate of 83% by actuarial analysis. Poor systolic function of the nonaneurysmal ventricular segments was the strongest and the only independent predictor of operative mortality among the clinical, hemodynamic, angiographic and electrophysiologic variables analyzed by stepwise logistic regression.
Ventricular tachycardia recurred early in four of the six patients in whom the endocardial resection was limited to a small area for technical reasons. Twelve patients, including 10 with sustained ventricular tachycardia still inducible by postsurgical programmed electrical stimulation, were discharged receiving antiarrhythmic drugs that had been tried unsuccessfully before surgery. During a mean follow-up period of 25 ± 15 months, nonfatal sustained ventricular tachycardia recurred in two patients after discharge. Inadequate endocardial resection was a significant predictor of arrhythmia recurrence.
- Received August 6, 1985.
- Revision received January 10, 1986.
- Accepted January 29, 1986.
- American College of Cardiology Foundation