Author + information
- Received December 13, 1985
- Revision received April 8, 1986
- Accepted April 29, 1986
- Published online September 1, 1986.
- ↵‡Address for reprints: Michael R. Rosen, MD, Department of Pharmacology, College of Physicians and Surgeons of Columbia University, 630 West 168th Street, New York, New York 10032.
Standard microelectrode techniques were used to study bigeminal rhythms occurring during otherwise stable triggered activity in ouabain-toxic canine Purkinje fibers. The basis for the bigeminy appeared to be an al-ternans phenomenon in the delayed afterdepolarizations that induced the triggered activity, as well as in the maximal diastolic potential. The occurrence of bigeminy, previously thought to result from reentry, from single delayed afterdepolarizations coupled to a triggered action potential or from parasystole, can also be considered a manifestation of sustained triggered activity.
- Received December 13, 1985.
- Revision received April 8, 1986.
- Accepted April 29, 1986.
- American College of Cardiology Foundation